Results 61 to 70 of about 11,028,780 (364)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Hiding Contextual Information for Defending a Global Attacker

IEEE Access, 2018
As wireless sensor networks are mostly deployed in harsh and hostile environments, lack of human maintenance, it has become a severe challenge to offer security or privacy service, especially when facing a powerful attacker.
Qian Zhou, Xiaolin Qin, Xiaojun Xie
doaj   +1 more source

Unilateral Invasions of Privacy [PDF]

, 2016
Most people seem to agree that individuals have too little privacy, and most proposals to address that problem focus on ways to give those users more information about, and more control over, how information about them is used.
Ford, Roger Allan
core   +2 more sources

Privacy Implications of In-Network Aggregation Mechanisms for VANETs [PDF]

, 2011
Research on vehicular ad hoc networks (VANETs) is active and ongoing. Proposed applications range from safety applications, and traffic efficiency applications to entertainment applications. Common to many applications is the need to disseminate possibly
Dietzel, Stefan
core   +4 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Optimal Forgery and Suppression of Ratings for Privacy Enhancement in Recommendation Systems

Entropy, 2014
Recommendation systems are information-filtering systems that tailor information to users on the basis of knowledge about their preferences. The ability of these systems to profile users is what enables such intelligent functionality, but at the same ...
Javier Parra-Arnau, David Rebollo-Monedero, Jordi Forné   +2 more
doaj   +1 more source

A novel and highly efficient botnet detection algorithm based on network traffic analysis of smart systems

International Journal of Distributed Sensor Networks, 2022
In smart systems, attackers can use botnets to launch different cyber attack activities against the Internet of Things. The traditional methods of detecting botnets commonly used machine learning algorithms, and it is difficult to detect and control ...
Li Duan, Jingxian Zhou, You Wu, Wenyao Xu   +3 more
doaj   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

SMS-Based Medical Diagnostic Telemetry Data Transmission Protocol for Medical Sensors

Sensors, 2011
People with special medical monitoring needs can, these days, be sent home and remotely monitored through the use of data logging medical sensors and a transmission base-station.
Tai-Hoon Kim, Ben Townsend, Jemal Abawajy   +2 more
doaj   +1 more source

Global Education Industry - Exploring the state of affairs in Austria

Seminar.net, 2021
Digitization initiatives in the field of education always correspond with developments in the education industry. In recent years, globally networked development dynamics have emerged that are essentially characterized by an education-industrial complex ...
English English, Reinhold Madritsch
doaj   +1 more source