Results 91 to 100 of about 33,602,714 (380)

Information processing in biological molecular machines

, 2020
Biological molecular machines are bi-functional enzymes that simultaneously catalyze two processes: one providing free energy and second accepting it. Recent studies show that most protein enzymes have a rich dynamics of stochastic transitions between ...
Chelminiak, Przemyslaw, Kurzynski, Michal   +1 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Influence of Environmental Spatial Layout on Perceived Lightness

i-Perception, 2011
It is obvious that perceived lightness of a surface depends on the surrounding luminance distribution in 2D and 3D. These effects are usually explained by the mechanisms at relatively low level of visual system.
Kei Kanari, Makoto Inagami, Hirohiko Kaneko   +2 more
doaj   +1 more source

Artificial and Natural Genetic Information Processing [PDF]

, 2017
Conventional methods of genetic engineering and more recent genome editing techniques focus on identifying genetic target sequences for manipulation.
Witzany, Guenther
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Information Processing

, 2011
Information processing broadly refers to the mental activity emerging from processes the human mind engages in while processing information encountered in an individual’s environment. These mental processes have become particularly important to study in the context of communication research because features of communication-related stimuli— present in ...
  +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Kans-Unet Model and Its Application in Image Patch-Shaped Detection

IEEE Access
This study proposes a new detection method Kans-Unet, which combines Kans and U-net architecture. Specifically, the method embeds a convolution module based on Kans (Kan-Conv) in the encoder. The module applies a learnable activation function at the edge
Xingsu Li, Zhong Li, Jianping Huang, Ying Han, Kexin Zhu, Bo Hao, Junjie Song, Yumeng Huo   +7 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Relaxed uncertainty relations and information processing

, 2009
We consider a range of "theories" that violate the uncertainty relation for anti-commuting observables derived in [JMP, 49, 062105 (2008)]. We first show that Tsirelson's bound for the CHSH inequality can be derived from this uncertainty relation, and ...
Steeg, Greg Ver, Wehner, Stephanie
core   +2 more sources