Results 101 to 110 of about 18,320,280 (211)

Adventures in Maze Folding Art

open access: yes, 2020
© 2020 Information Processing Society of Japan. Every orthogonal graph, extruded orthogonally from a rectangle, can be folded from a rectangle of paper a constant factor larger.
Demaine, Martin L   +3 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

MetaLA : unified optimal linear approximation to softmax attention map [PDF]

open access: yes
38th Conference on Neural Information Processing Systems (NeurIPS 2024), 10-15 December 2024, Vancouver, Canada202506 bcchAccepted ManuscriptOthersCAS Project for Young Scientists in Basic Research; National Distinguished Young Scholars; National Natural
Qiao, Y   +9 more
core  

Couples’ Factors Affecting Antenatal Care Utilization in Nigeria

open access: yesAdvances in Public Health
Conclusions: Various factors influenced the ANC utilization. However, the educational levels of the couple, their place of residence, wealth status, and exposure to media remained significant.
Joyce Nnenna Agbo   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Dictionary of data processing. : including applications in industry, administration and business. /

open access: yes, 1973
First ed. by L. Trollhann and A.
Trollhann, Lilian.,Dictionary of information processing.   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Deep survival analysis in multimodal medical data: a parametric and probabilistic approach with competing risks

open access: yesScientific Reports
Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology.
Alba Garrido   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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