Results 101 to 110 of about 33,602,714 (380)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Eigenvalue Based Detection by Combining Eigenvector-Correlated Signal in Low SNR Environment

open access: yesIET Signal Processing
Eigenvalue detection is extensively utilized in numerous applications, including spectrum sensing in cognitive radio. However, the characteristics of the Tracy–Widom (TW2) distribution and its lack of accurate close-form expression limit the detection ...
Wei Ge   +4 more
doaj   +1 more source

Effects of foveal information processing [PDF]

open access: yes
The scanning behavior of pilots must be understood so that cockpit displays can be assembled which will provide the most information accurately and quickly to the pilot.
Harris, R. L., Sr.
core   +1 more source

Experimental quantum information processing with 43Ca+ ions

open access: yes, 2008
For quantum information processing (QIP) with trapped ions, the isotope 43Ca+ offers the combined advantages of a quantum memory with long coherence time, a high fidelity read out and the possibility of performing two qubit gates on a quadrupole ...
C. F. Roos   +4 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Convolutional Neural Network Based Joint Estimation of Direction of Arrival and Polarisation Parameters

open access: yesIET Radar, Sonar & Navigation
In this paper, a convolutional neural network (CNN) based algorithm for joint estimation of direction of arrival (DOA) and polarisation parameters is introduced.
Pangzhe Li, Dexiu Hu, Chuang Zhao
doaj   +1 more source

An Improved Method for Named Entity Recognition and Its Application to CEMR

open access: yesFuture Internet, 2019
Named Entity Recognition (NER) on Clinical Electronic Medical Records (CEMR) is a fundamental step in extracting disease knowledge by identifying specific entity terms such as diseases, symptoms, etc.
Ming Gao   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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