Results 91 to 100 of about 778,107 (265)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Information professionals: core competencies and professional development

Information Research: An International Electronic Journal, 2007
Introduction. We discuss the concept of core competencies applied to policies for teaching and training information professionals, particularly librarians. Method. Sixty graduates of the Institute were employed as information professionals. These sixty were asked to attribute degrees of importance to specific items associated with knowledge and skills ...
Flávia Ferreira, Joanice Nascimento Santos, Lucyana Nascimento, Ricardo Sodré Andrade, Susane Barros, Jussara Borges, Helena Pereira da Silva, Othon Jambeiro, Fábio Ferreira, Bethany Lynn Letalien   +9 more
openaire   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Novel hybrid intelligence model for early Alzheimer's diagnosis utilizing multimodal biomarker fusion

Informatics in Medicine Unlocked
One of the significant causes of dementia and a leading peril to global public health is Alzheimer's disease (AD), which calls for early and accurate diagnosis.
Shehu Mohammed, Neha Malhotra, Arun Singh, Awad M. Awadelkarim, Shakeel Ahmed, Saiprasad Potharaju   +5 more
doaj   +1 more source

Opportunities of Semiconducting Oxide Nanostructures as Advanced Luminescent Materials in Photonics

Advanced Materials, EarlyView.
The review discusses the challenges of wide and ultrawide bandgap semiconducting oxides as a suitable material platform for photonics. They offer great versatility in terms of tuning microstructure, native defects, doping, anisotropy, and micro‐ and nano‐structuring. The review focuses on their light emission, light‐confinement in optical cavities, and
Ana Cremades, Pedro Hidalgo, David Maestre, Ruth Martínez‐Casado, Emilio Nogales, Beatriz Rodríguez, G. Cristian Vásquez, Bianchi Méndez   +7 more
wiley   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Two‐Photon 3D Printing of Functional Microstructures Inside Living Cells

Advanced Materials, EarlyView.
This study demonstrates 3D printing inside living cells by using two‐photon photo‐lithography. A bio‐compatible photoresist is injected into cells and selectively polymerized with a femtosecond laser, creating custom‐shaped intracellular structures with submicron resolution.
Maruša Mur, Aljaž Kavčič, Uroš Jagodič, Rok Podlipec, Matjaž Humar   +4 more
wiley   +1 more source

Enhanced Community Detection via Convolutional Neural Network: A Modified Approach Based on MRFasGCN Algorithm

IEEE Access
Community detection is a very important research topic in the field of Social Network Analysis. Lots of researchers are working in this field due to its applications in various fields like medicine, social, Business, Marketing, and research.
Puneet Kumar, Dalwinder Singh, Mamoona Humayun, Ali Alqazzaz, Arun Malik, Ibrahim Alrashdi, Isha Batra, Ghadah Naif Alwakid   +7 more
doaj   +1 more source

Multiscale Acoustic Bubble Actuators Using Bioinspired Liquid‐Repellent Microstructures

Advanced Materials Technologies, EarlyView.
The article presents multiscale acoustic bubble actuators using bioinspired liquid‐repellent microstructures, enabling programmable trapping, pumping, mixing, and precise flow control. Mimicking springtail microstructures, these scalable actuators (200 µm–1 mm) offer multifunctionality in all‐in‐one devices, letter‐shaped arrays, and 3D cube ...
Cem Balda Dayan, Nima Mahkam, Nihal Olcay Dogan, Ville Liimatainen, Defne Hiz, Aleyna Ilgezdi, Daniel Razansky, Amirreza Aghakhani, Metin Sitti   +8 more
wiley   +1 more source