Results 111 to 120 of about 1,061,926 (267)
System Construction of Athlete Health Information Protection Based on Machine Learning Algorithm.
Biomed Res Int, 2022 Liu L, Fan X.
europepmc +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Безопасность информационных технологий, 2011 In the paper possibility of application of parametrical aerials in complexes on protection of the speech information is considered.
O. S. Varlamov
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Software for audit of information protection system of the organization
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 На основе требований к системе защиты информации, представленных в приказе Оперативно-аналитического центра при Президенте Республики Беларусь от 30.08.2013 № 62, и положений СТБ ISO/IEC 27001-2016 составлен перечень вопросов и разработано программное ...
V. A. Boiprav, V. V. Kovalev, L. L. Utin
doaj
Protective Encoding of Information Carriers
Intellectual ArchiveAll projects in this group of technical solutions are based on a single method of encoding and subsequent identification of the encoded element's recording. The essence of the principle lies in applying a coding coating (or its technological equivalent) to the protected object and subsequently measuring the thickness of this coating.
openaire +1 more source