Results 71 to 80 of about 3,985,301 (303)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The quality maturity model: assessing organisational quality culture in academic libraries [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityAcademic libraries operate in a fluid environment, where they must provide, and demonstrate that they provide, a high quality service that is focussed on ...
Wilson, Frances
core  

SUCCESS DETERMINANTS OF THE REGIONAL GOVERNMENT INFORMATION SYSTEM ON USEFULNESS IN DECISION MAKING OF NTB PROVINCIAL GOVERNMENT [PDF]

open access: yesEurasia: Economics & Business, 2023
The aim of the research is to evaluate whether SIPD can be said to be successful and has a positive impact on usefulness in decision making using the DeLone and McLean Model (2003).
Lodayah Z.M., Akram, Muhsyaf S.A.
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Information Services for Supporting Quality Management in Healthcare [PDF]

open access: yes, 2006
In today’s world, society and the economy are placing an increasing emphasis on information and its quality. Quality and information management are interrelated, and advances in information and communication technology have led to a re-assessment of many
Kostagiolas, Petros A.
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Fake News or Weak Science? Visibility and Characterization of Antivaccine Webpages Returned by Google in Different Languages and Countries

open access: yesFrontiers in Immunology, 2018
The 1998 Lancet paper by Wakefield et al., despite subsequent retraction and evidence indicating no causal link between vaccinations and autism, triggered significant parental concern. The aim of this study was to analyze the online information available
Nadia Arif   +10 more
doaj   +1 more source

Can Siskeudes support village governance in Aceh Province of Indonesia?

open access: yesCogent Business & Management, 2020
This study is to investigate whether the village financial system (Siskeudes) can realize governance. This test was carried out using the success model of the DeLone and McLean system.
Mirna Indriani   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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