Results 151 to 160 of about 4,645,295 (283)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
On how correlations between excitatory and inhibitory synaptic inputs maximize the information rate of neuronal firing. [PDF]
Front Comput Neurosci, 2014 Puzerey PA, Galán RF.
europepmc +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Measuring the information content of customer foreign exchange orders
, 2014 This paper investigates whether customer order flow conveys information about future foreign exchange (FX) prices. We use a unique data set from a leading Australian commercial bank that records every FX trade made by the bank in the spot Australian ...
Rosov, S, Foster, FD
core
Iranian Journal of Information Processing & Management, 2014 Electronic information resources (EIR) play an important role in the process of education and research. The aim of this study was to analyze the status of adoption of electronic information resources (EIR) by Iranian Knowledge and Information Science ...
Afshin Hamdipour, Zahed Bigdeli
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Exchange Rate Volatility and the Mixture of Distribution Hypothesis [PDF]
This paper sheds new light on the mixture of distribution hypothesis by means of a study of the weekly exchange rate volatility of the Norwegian krone. In line with other studies we find that the impact of information arrival on exchange rate volatility ...
Dagfinn, RIME +2 more
core
The quadratic decaying property of the information rate function states that, given a fixed conditional distribution pY|X , the mutual information between the (finite) discrete random variables X and Y decreases at least quadratically in the Euclidean ...
Cao, MX, Tomamichel, M
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Securities Pricing with Information-Sensitive Discounting [PDF]
In this paper incomplete-information models are developed for the pricing of securities in a stochastic interest rate setting. In particu- lar we consider credit-risky assets that may include random recovery upon default.
Andrea Macrina, Priyanka A. Parbhoo
core