Results 101 to 110 of about 18,873,871 (290)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

The Kansas Information Technology Architecture

open access: yes, 2009
Version 11.2; application/pdf; Cover title.; "12/28/2009."; "This Architecture provided to the State of Kansas by the Kansas Technical Architecture Review Board (KTARB), presented to and approved by the Information Technology Executive ...
Kansas. Information Technology Office.
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Community Engagement in Research and Design of a Transgender Health Information Resource. [PDF]

open access: yesAppl Clin Inform, 2023
Morse B   +7 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

INFORMATION RESOURCES EFFECT ON THE QUALITY COMPARATIVE ANALYSIS OF THE MECHANISM OF STATE-PRIVATE PARTNERSHIP IN THE DEVELOPMENT OF TRANSPORT INFRASTRUCTURE

open access: yesВестник университета, 2017
In the article, authors considered value of information resource as bases of high-quality comparison of public-private partnership at development of transport infrastructure at different social and economic stages of development of Russia.
T. Bogdanova
doaj  

LitCovid in 2022: an information resource for the COVID-19 literature. [PDF]

open access: yesNucleic Acids Res, 2023
Chen Q   +7 more
europepmc   +1 more source

Other title: Resource guide

open access: yes, 1981
"The objective of each Regional Occupational Information Workshop is to explore and analyze labor market and occupational information. This Resource Guide was produced by the KOICC to facilitate the workshop participant during the session and ...
Kansas Occupational Information Coordinating Committee.
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

PRINCIPLES OF INTERNET TECHNOLOGIES AS BASIS OF UNIFIED EDUCATIONAL ENVIRONMENT FORMATION

open access: yesІнформаційні технології і засоби навчання, 2010
Principles of creation of the information systems of education with use of Internet technologies for forming the unified educational environment are resulted, approaches to creation and support of portals are expounded in the article.
Natalia T. Zadorozhna   +2 more
doaj  

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