Results 81 to 90 of about 1,090,405 (255)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

LitCovid in 2022: an information resource for the COVID-19 literature. [PDF]

Nucleic Acids Res, 2023
Chen Q, Allot A, Leaman R, Wei CH, Aghaarabi E, Guerrerio JJ, Xu L, Lu Z.   +7 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Co-design of the Transgender Health Information Resource: Web-Based Participatory Design. [PDF]

J Particip Med, 2023
Morse B, Soares A, Ytell K, DeSanto K, Allen M, Holliman BD, Lee RS, Kwan BM, Schilling LM.   +8 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Information Resource "Mechanics and Mechanical Engineering in the Republic of Belarus" as a Basis of Information Support of Innovation Development Mechanical Engineering Complex of Belarus

Механика машин, механизмов и материалов, 2010
Submitted an electronic information resource "Mechanics and Mechanical Engineering in the Republic of Belarus". Adduces the sources of its formation, the types of documents included, features, functions, specifications and features.
Yu.N. Vrazhkin , S.V. Rusan , V.N. Stukachou, G.O. Lauzhel   +3 more
doaj  

Specificity of the design of the development of an information resource and an electronic register of scientific professional publications in the context of digitalization of the scientific field

Innovation and Sustainability
The digitization of the scientific sphere opens up new opportunities for preserving, analyzing, and accessing information. At the same time, it creates new challenges related to the development of effective tools for data management.
L. Nikiforova, I. Dohtieva, S. Zharinov
doaj   +1 more source

YouTube as an Information Resource for Persons Interested in Septoplasty and/or Turbinoplasty. [PDF]

J Rhinol, 2022
Jeong CY, Lee IH, Kim DH, Kim SW, Kim SW.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

FUNCTIONAL ORGANIZATIONS CONCEPT OF THE POLYTECHNIC UNIVERSITY TYPICAL INFORMATION RESOURCES INTERNET PORTAL

Ìнформаційні технології в освіті, 2010
Functional organizations concept of the polytechnic university typical information resources Internet portal are presented by subsystems, services, WEB-resources and information areas.
V. Babenko, T. Babina, O. Gabzovska, A. Savitsky   +3 more
doaj