Results 61 to 70 of about 18,873,871 (290)

A DATABASE ON TRANSLATIONAL ENHANCERS TO SUPPORT EXPERIMENTS WITH TRANSGENIC PLANTS

open access: yesВавиловский журнал генетики и селекции, 2014
A database on translational enhancers providing additional control of foreign gene expression at the mRNA translation level has been developed. It contains structured information on the presence of enhancers located within mRNAs, which control gene ...
O. G. Smirnova   +2 more
doaj  

Specificity of the design of the development of an information resource and an electronic register of scientific professional publications in the context of digitalization of the scientific field

open access: yesInnovation and Sustainability
The digitization of the scientific sphere opens up new opportunities for preserving, analyzing, and accessing information. At the same time, it creates new challenges related to the development of effective tools for data management.
L. Nikiforova, I. Dohtieva, S. Zharinov
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Designing a Mini-Program for Culture Learning and Creative Product Customization: DIY RADP

open access: yesDigital Presentation and Preservation of Cultural and Scientific Heritage, 2019
Taking Chinese royal architecture decorative patterns as an example, this paper explores an overall socioeconomic framework of culture learning and culture creative product customization as well as the technological framework for developing a WeChat mini-
Xiaoshuang Jia   +5 more
doaj   +1 more source

Philippines 1:50,000 [cartographic material].

open access: yes, 1988
Edn. 1 - DMATC. Topographic map series of the Philippines showing transportation, communication, vegetation, land use, water features, populated places, built-up areas and some public buildings. Relief shown by soundings, contours and spot heights.; Each
Philippines. National Mapping and Resource Information Authority.
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Designing Edutainment Games for Intangible Cultural Heritage: the BNREG Project

open access: yesDigital Presentation and Preservation of Cultural and Scientific Heritage, 2019
This paper presents the preliminary investigation and game design process of Beijing Nursery Rhyme Edutainment Game (hereinafter referred to as BNREG), from which we think edutainment concept can provide an innovative gamification method for the impart ...
Xiaoshuang Jia   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Resource News issue: summer 1998 [PDF]

open access: yes, 1998
The summer 1998 issue of Resource News, which was a community newsletter from the Child Care Resource and Referral office of Washington County ...
Washington County Child Care Resource and Referral (Or.)
core   +1 more source

Information Resource "Mechanics and Mechanical Engineering in the Republic of Belarus" as a Basis of Information Support of Innovation Development Mechanical Engineering Complex of Belarus

open access: yesМеханика машин, механизмов и материалов, 2010
Submitted an electronic information resource "Mechanics and Mechanical Engineering in the Republic of Belarus". Adduces the sources of its formation, the types of documents included, features, functions, specifications and features.
Yu.N. Vrazhkin   +3 more
doaj  

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