Results 51 to 60 of about 4,571,543 (326)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

DYNAMIC ONTOLOGY BASED RETRIEVAL AND ANALYSIS OF INFORMATION

Современные информационные технологии и IT-образование, 2018
RDF ontologies are proposed as modelling pattern for associations of innovation cycles being performed by science-intensive technical products. An appropriate ontology is applied as framework of personalized archives of scientific and engineering ...
Andrey P. Gagarin, Vladimir V. Serdyukov
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Information Resource "Mechanics and Mechanical Engineering in the Republic of Belarus" as a Basis of Information Support of Innovation Development Mechanical Engineering Complex of Belarus

Механика машин, механизмов и материалов, 2010
Submitted an electronic information resource "Mechanics and Mechanical Engineering in the Republic of Belarus". Adduces the sources of its formation, the types of documents included, features, functions, specifications and features.
Yu.N. Vrazhkin , S.V. Rusan , V.N. Stukachou, G.O. Lauzhel   +3 more
doaj  

INFORMATION RESOURCES ANALYSIS IN ELECTRONIC CONTENT COMMERCE SYSTEMS [PDF]

Applied Computer Science, 2016
The article is dedicated to the development of unified methods and soft-ware tools for processing information resources in the electronic content commerce systems.
Lyubomyr CHYRUN, Victoria VYSOTSKA, Rostik LABA   +2 more
doaj  

Fair and Efficient Resource Allocation with Partial Information [PDF]

, 2021
Daniel Halpern, Nisarg Shah
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

FUNCTIONAL ORGANIZATIONS CONCEPT OF THE POLYTECHNIC UNIVERSITY TYPICAL INFORMATION RESOURCES INTERNET PORTAL

Ìнформаційні технології в освіті, 2010
Functional organizations concept of the polytechnic university typical information resources Internet portal are presented by subsystems, services, WEB-resources and information areas.
V. Babenko, T. Babina, O. Gabzovska, A. Savitsky   +3 more
doaj  

Specificity of the design of the development of an information resource and an electronic register of scientific professional publications in the context of digitalization of the scientific field

Innovation and Sustainability
The digitization of the scientific sphere opens up new opportunities for preserving, analyzing, and accessing information. At the same time, it creates new challenges related to the development of effective tools for data management.
L. Nikiforova, I. Dohtieva, S. Zharinov
doaj   +1 more source

Database «Uncensored Siberian periodicals (1920-1990)»

Библиосфера, 2016
The article discusses the problem of forming an electronic database of uncensored periodicals of the Siberian region. The modern state and prospects of applying information technologies to study samizdat are highlighted.
E. N. Savenko, N. A. Balytkina
doaj   +1 more source