Results 31 to 40 of about 2,234,996 (219)

The oldest medical library in Siberia (to the 70th anniversary of the Scientific-Medical Library of Siberian State Medical University)

open access: yesБюллетень сибирской медицины, 2005
The history of the oldest medical library in Siberia has been presented. There is data of the stock, information resources and the basic activity directions.
N. V. Molodtsova
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Agricultural Information Needs and Resources of Smallholder Sugarcane Farmers in Swaziland

open access: yesLibri
The sugar industry is the dominant agricultural sector in Swaziland’s economy, contributing significantly to the gross domestic product. Provision of relevant and timely information to smallholder sugarcane farmers is crucial for them to have a ...
Dlamini Nkosinathi M., Ngulube Patrick
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

THE INNOVATIVE INFRASTRUCTURE OF ECONOMIC DEVELOPMENT IN THE FRAMEWORK OF INTERNATIONAL DIGITAL TRANSFORMATION [PDF]

open access: yesBaltic Journal of Economic Studies, 2018
The development of the innovative digital system, as an important part of the market infrastructure, partly reflects the overall economic level of the country, but its further positive dynamics with the growth of the national economy determines the ...
Sergii Kolodynskyi   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Philosophy of creating information resources

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу
Information has become the main driver of modern society, affecting all spheres of life, from education and science to business and communication. In the context of the global digital transformation, the amount of data generated on a daily basis requires
N.Ya. Marchyshyn
doaj   +1 more source

Current situation and analysis on the distribution and utilization of resources in agricultural literature and information of Zhejiang

open access: yes浙江大学学报. 农业与生命科学版, 2002
The paper analysed the present problems on resources in agricultural literature and information of Zhejiang, based on the investigation of libraries related to agriculture and websites contributed by ourselves, several suggestion was given finally.
SHEN Ying
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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