Information Resources Importance and Format Inclination of Science and Technology Researchers
This study examined important information resources and format inclination of information resources utilized by science and technology (S&T) researchers as they acquire information in the course of their projects.
Olayinka B. Makinde Makinde+2 more
doaj
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
COMMERCIALIZATION OF INNOVATIVE ACTIVITIES AND ESSENCE OF INNOVATIVE ENTREPRENEURSHIP
The conceptual framework of commercialization in the market system is revealed. The essence of the innovation business in the regulation of the commercial innovative activities is analyzed.
Boris М. Getman+2 more
doaj
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Retracted: Value Exploration and Application of Digital Archive Information Resources under the Information Ecological Environment. [PDF]
Environmental And Public Health JO.
europepmc +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
'ZOOMing' in on Consulting with Children and Parents Remotely to Co-Create Health Information Resources. [PDF]
Saron H+8 more
europepmc +1 more source
Iron ore (summary of information as to the present and prospective iron‐one supplics of the world). Part 1, United Kingdom (pp. 237, 6s.); Pt. 2, British Africa (pp. 76, 3s.); Pt. 3, British America (pp. 106,4s.). Imperial mineal resources bureau, London: H. M. Stationery Office, 1922. [PDF]
H. LOUIS
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
The article deals with controversial issues related to the use of public information on the Internet, the interpretation of the terms “access to information” and “use of information”.
Anna G. Donskikh
doaj +1 more source