Results 81 to 90 of about 19,385,628 (381)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

DESIGNING OF SECONDARY SCHOOL INFORMATION ENVIRONMENT

open access: yesІнформаційні технології і засоби навчання, 2010
In the article the concept of «secondary school information environment» is considered, the problems concerning its creation are analyzed. There are determined purposes, problems and principles of information environment creation at school.
Oksana Ye. Kravchina
doaj  

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

A Model for Evaluating Damage Inflicted Dye Destructive Events in the Computer Information System

open access: yesБезопасность информационных технологий, 2010
Here we present a model to evaluate the mean expectation of damage inflicted by destructive events in the computer information system. A condition of damage reduction is deduced. Some ways how to guarantee supply of this condition are presented.
S. V. Zapechnikov
doaj  

Philosophy of creating information resources

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу
Information has become the main driver of modern society, affecting all spheres of life, from education and science to business and communication. In the context of the global digital transformation, the amount of data generated on a daily basis requires
N.Ya. Marchyshyn
doaj   +1 more source

Effects of corruption risks on access to information resources: the question

open access: yesПроблеми Законності, 2015
The article examines the impact of actual corruption risks in providing access to information resources. Defined objective and subjective factors contributing to the corruption risks and the ways of their reduction.
О. Б. Червякова
doaj   +1 more source

Integrating Renewable Energy Resources into the Smart Grid: Recent Developments in Information and Communication Technologies

open access: yesIEEE Transactions on Industrial Informatics, 2018
Rising energy costs, losses in the present-day electricity grid, risks from nuclear power generation, and global environmental changes are motivating a transformation of the conventional ways of generating electricity. Globally, there is a desire to rely
M. H. Rehmani   +4 more
semanticscholar   +1 more source

Delayed inhibition of an anticipatory action during motion extrapolation [PDF]

open access: yes, 2010
Background: Continuous visual information is important for movement initiation in a variety of motor tasks. However, even in the absence of visual information people are able to initiate their responses by using motion extrapolation processes ...
Marinovic, Welber   +4 more
core   +4 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

FINANCIAL STATEMENTS OF MULTILEVEL SYSTEM OF CONSUMER COOPERATION IN UKRAINE, ITS INFORMATIONAL COMPLIANCE WITH MODERN EUROPEAN REQUIREMENTS

open access: yesUSV Annals of Economics and Public Administration, 2016
More than 120 countries use the International Financial Reporting Standards (IFRS) and the International Accounting Standards (IAS). The Association Agreement between Ukraine and the EU obliges Ukraine to European convergence of accounting.
Stepan KOSHKAROV
doaj  

Home - About - Disclaimer - Privacy