Results 51 to 60 of about 2,579,110 (275)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Recursos web sobre literatura grisa

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
Recull comentat de recursos en línia, d’abast general, relacionats amb la 'literatura grisa' o documentació de difusió restringida, útils per a treballar amb ella.
Turiel, Josep
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Resources for Information Literacy Instruction in the Sciences.

Issues in Science and Technology Librarianship, 2008
This bibliography contains a collection of web sites and online resources that pertain to information literacy sources for scientific disciplines. This web bibliography, or "webliography", contains links and descriptions of web sites that cover general ...
Maribeth Slebodnik, Annie Zeidman-Karpinski   +1 more
doaj   +1 more source

MATHEMATICAL MODEL FOR CALCULATION OF INFORMATION RISKS FOR INFORMATION AND LOGISTICS SYSTEM [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2015
Subject of research. The paper deals with mathematical model for assessment calculation of information risks arising during transporting and distribution of material resources in the conditions of uncertainty. Meanwhile information risks imply the danger
A. G. Korobeynikov, A. Y. Grishentsev, I. E. Komarova, D. Y. Ashevsky, S. A. Aleksanin, G. L. Markina   +5 more
doaj   +1 more source

Physicians' Perception of Drug Information Resources in the Emirate of Abu Dhabi-UAE *

, 2013
Objectives: To determine physicians’ preferences for different drug information resources in the United Arab Emirates. Methods: A questionnaire survey to determine preferences for different drug information resources was created and sent electronically ...
Hadaya Gharibyar, Y. Sharif, Kefah Al Qawasme, S. Fahmy   +3 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Modernization of the approach to usage of region’s budget resources in the conditions of information economy development

, 2017
The purpose of the article is to substantiate the necessity and to develop recommendations for modernizing the approach for usage of region's budget resources in the conditions of the information economy creation.
Aleksey V. Bogoviz, Y. Ragulina, Anna V. Komarova, A. Bolotin, S. Lobova   +4 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source