Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Connecting Human and Information Resources in the Generation of Competitive Advantage
Abstract A key trend in recent decades is a growing standardisation of tangible digital resources. This trend coexists with development in the most advanced organisations of high-level technological, human and organisational resources teams built around advanced digital solutions.
Sergio Camisón-Haba +2 more
openaire +4 more sources
Librarian Recommended: A Survey of Engineering Education Resources in Library Research Guides
Through content analysis, this study identifies the information resources frequently included in Engineering Education Research (EER) library research guides from universities with very high research activity.
Allyson Wood
doaj +1 more source
Measuring quality, reputation and trust in online communities
In the Internet era the information overload and the challenge to detect quality content has raised the issue of how to rank both resources and users in online communities.
Cimini, Giulio, Liao, Hao, Medo, Matus
core +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Memory encoding of syntactic information involves domain-general attentional resources: Evidence from dual-task studies [PDF]
Evelien Heyselaar, Katrien Segaert
openalex +3 more sources
Exploring general practitioners’ perception of the value of natural history information and their awareness and use of guidelines’ resources to support antibiotic prescribing for self-limiting infections: a qualitative study in Australian general practice [PDF]
Kwame Peprah Boaitey +3 more
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Challenges in multidisciplinary cancer care among general surgeons in Canada
Background While many factors can influence the way that cancer care is delivered, including the way that evidence is packaged and disseminated, little research has evaluated how health care professionals who manage cancer patients seek and use this ...
McLeod Robin S +4 more
doaj +1 more source

