Results 101 to 110 of about 10,035,302 (334)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

XPIR : Private Information Retrieval for Everyone

open access: yesProceedings on Privacy Enhancing Technologies, 2016
A Private Information Retrieval (PIR) scheme is a protocol in which a user retrieves a record from a database while hiding which from the database administrators.
C. A. Melchor   +3 more
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

A New Image Oversampling Method Based on Influence Functions and Weights

open access: yesApplied Sciences
Although imbalanced data have been studied for many years, the problem of data imbalance is still a major problem in the development of machine learning and artificial intelligence. The development of deep learning and artificial intelligence has further
Jun Ye, Shoulei Lu, Jiawei Chen
doaj   +1 more source

Bibliometric-Enhanced Information Retrieval [PDF]

open access: yes, 2014
6 pages, accepted workshop proposal for ECIR ...
Andrea Scharnhorst   +4 more
openaire   +4 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

open access: yesFEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez   +8 more
wiley   +1 more source

Clinical entity-aware domain adaptation in low resource setting for inflammatory bowel disease

open access: yesFrontiers in Artificial Intelligence
The digitization of healthcare records has revolutionized medical research and patient care, with electronic health records (EHRs) containing a wealth of structured and unstructured data.
Sumam Francis   +5 more
doaj   +1 more source

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