Results 81 to 90 of about 1,119,505 (284)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Privacy-Preserving Data Sharing and Computing for Outsourced Policy Iteration with Attempt Records from Multiple Users

open access: yesApplied Sciences
Reinforcement learning is a machine learning framework that relies on a lot of trial-and-error processes to learn the best policy to maximize the cumulative reward through the interaction between the agent and the environment.
Bangyan Chen, Jun Ye
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Seagrass and hydrographic data for the Mediterranean Sea

open access: yesData in Brief, 2019
The dataset includes 1,771 locations of major seagrass families (Cymodoceaceae, Zosteraceae, Posidoniaceae, Hydrocharitaceae, Ruppiaceae), which are further divided into the species they include, as well as 1,284 locations of seagrass absence ...
Dimitrios Effrosynidis   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The Capacity of Private Information Retrieval

open access: yes, 2017
In the private information retrieval (PIR) problem a user wishes to retrieve, as efficiently as possible, one out of $K$ messages from $N$ non-communicating databases (each holds all $K$ messages) while revealing nothing about the identity of the desired
Jafar, Syed A., Sun, Hua
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

FAQchat as in Information Retrieval system [PDF]

open access: yes, 2005
A chatbot is a conversational agent that interacts with users through natural languages. In this paper, we describe a new way to access information using a chatbot.
Abu Shawar, B.A.   +2 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Routing Protocol for Underwater Wireless Sensor Networks Based on a Trust Model and Void-Avoided Algorithm

open access: yesSensors
Underwater wireless sensor networks have a wide range of application prospects in important fields such as ocean exploration and underwater environment monitoring. However, the influence of complex underwater environments makes underwater wireless sensor
Jun Ye, Weili Jiang
doaj   +1 more source

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