Results 41 to 50 of about 1,119,505 (284)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Self-organization of the stock exchange to the edge of a phase transition: empirical and theoretical studies

Frontiers in Physics
Our study is based on the hypothesis that stock exchanges, being nonlinear, open and dissipative systems, are capable of self-organization to the edge of a phase transition.
Andrey Dmitriev, Andrey Dmitriev, Andrey Lebedev, Vasily Kornilov, Victor Dmitriev   +4 more
doaj   +1 more source

Transfer Learning for Named Entity Recognition in Financial and Biomedical Documents

Information, 2019
Recent deep learning approaches have shown promising results for named entity recognition (NER). A reasonable assumption for training robust deep learning models is that a sufficient amount of high-quality annotated training data is available.
Sumam Francis, Jordy Van Landeghem, Marie-Francine Moens   +2 more
doaj   +1 more source

Semi-supervised incremental learning with few examples for discovering medical association rules

BMC Medical Informatics and Decision Making, 2022
Background Association Rules are one of the main ways to represent structural patterns underlying raw data. They represent dependencies between sets of observations contained in the data. The associations established by these rules are very useful in the
Ricardo Sánchez-de-Madariaga, Juan Martinez-Romo, José Miguel Cantero Escribano, Lourdes Araujo   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The Audio Degradation Toolbox and its Application to Robustness Evaluation [PDF]

, 2013
We introduce the Audio Degradation Toolbox (ADT) for the controlled degradation of audio signals, and propose its usage as a means of evaluating and comparing the robustness of audio processing algorithms.
Ewert, S, International Society for Music Information Retrieval Conference (ISMIR 2013), MAUCH, M   +2 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Text Filtering through Multi-Pattern Matching: A Case Study of Wu–Manber–Uy on the Language of Uyghur

Information, 2019
Given its generality in applications and its high time-efficiency on big data-sets, in recent years, the technique of text filtering through pattern matching has been attracting increasing attention from the field of information retrieval and Natural ...
Turdi Tohti, Jimmy Huang, Askar Hamdulla, Xing Tan   +3 more
doaj   +1 more source

Affective Music Information Retrieval [PDF]

, 2015
Much of the appeal of music lies in its power to convey emotions/moods and to evoke them in listeners. In consequence, the past decade witnessed a growing interest in modeling emotions from musical signals in the music information retrieval (MIR ...
Wang, Hsin-Min, Wang, Ju-Chiang, Yang, Yi-Hsuan   +2 more
core  

Personalization via collaboration in web retrieval systems: a context based approach [PDF]

, 2003
World Wide Web is a source of information, and searches on the Web can be analyzed to detect patterns in Web users' search behaviors and information needs to effectively handle the users' subsequent needs.
Cool, Coon, Dix, Edwards, Goker, Goker, Goker, Goker, He, Hersh, Jansen, Mobasher, Pazzani, Resnick, Robertson, Robertson   +15 more
core   +1 more source