Results 101 to 110 of about 15,421,158 (251)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Fixed Asset Revaluation Motivations Les Motivations De Revaluation Des Immobilisation

open access: yes, 2019
The purpose of our research is to highlight, by means of case study, potential motivations that canbe behind asset revaluation. The results from this study indicate that the motivation that can bebehind the revaluation decision is to convey a faithful ...
ATIG, Toufik, BENYAMINA, Fatima Zohra
core   +1 more source

Helicobacter pylori: types of diseases, diagnosis, treatment and causes of therapeutic failure

open access: yesJournal of Mind and Medical Sciences, 2016
Acute upper gastrointestinal lesions have a multifactorial etiology but, regardless of the cause, they are related to mucosal barrier destruction. Since Helicobacter pylori induces a superficial chronic gastritis with the infiltration of neutrophils in ...
Cosmin Vasile Obleaga   +4 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Other title: Kansas Strategic Information Management Plan; Other title: State of Kansas Strategic Information Management Plan

open access: yes, 1997
application/pdf; Cover title.; "February 25, 1997."; "The Chief Information Architect (CIA), working with the Kansas Information Resources Council (KIRC)..."--Abstract, page ...
Kansas. Office of the Chief Information Architect.
core  

CHANGING BUSINESS ENVIRONMENT

open access: yesSosyal Ekonomik Araştırmalar Dergisi, 2003
Küresel ekonomik yapı iş dünyasının çevresel koşullarını dönüştürmektedir. Işletmeler hızla değişen çevresel ortama uygun yönetsel politikalar uygulayarak tepki vermektedir.
Süleyman AÇIKALIN
doaj   +2 more sources

ANALISIS IMPLEMENTASI SAK ETAP MENJADI SAK EP: STUDI KOMPARATIF PERUSAHAAN MANUFAKTUR DAN JASA

open access: yesRiset Akuntansi
This research aims to examine the effects of implementing the new financial accounting standard—Standar Akuntansi Keuangan Entitas Privat (SAK EP), or Financial Accounting Standards for Private Entities—on the financial reporting practices of two ...
Abhyasa Sulthan Madaharsa   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

La Calidad de la Información Fiscal en las Empresas del IBEX-35

open access: yesRevista de Contabilidad: Spanish Accounting Review, 2006
En el actual proceso de adaptación de la normativa española a las Normas Internacionales de Contabilidad, el futuro tratamiento contable del Impuesto sobre Sociedades supone mayores exigencias de información, lo que conlleva nuevas obligaciones formales ...
Julián Martínez Vargas   +1 more
doaj  

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