Results 121 to 130 of about 11,191,535 (322)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Symposium on information science. 8. An approach to the automated handling of chemical-biological data in a pharmaceutical firm [PDF]

, 1965
C W Durachta, Colin Schenk, Richard Dick, F M Sturtevant   +3 more
openalex   +1 more source

Geographic information science in the era of geospatial big data: A cyberspace perspective. [PDF]

Innovation (Camb), 2022
Liu X, Chen M, Claramunt C, Batty M, Kwan MP, Senousi AM, Cheng T, Strobl J, Arzu C, Wilson J, Bandrova T, Konecny M, Torrens PM, Zhang F, He L, Wang J, Ratti C, Kolditz O, Klippel A, Li S, Lin H, Lü G.   +21 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Symposium on information science. 3. Changing patterns of scientific periodical publication [PDF]

, 1965
G. Miles Conrad
openalex   +1 more source

Perceptions of employers in South Africa on library and information science graduates' skills, knowledge and competencies on digital scholarship. [PDF]

Heliyon, 2023
Sibiya PT, Ngulube P.
europepmc   +1 more source

Connecting teachers and students with science and scientists: The science learning hub [PDF]

, 2010
National and international data is raising concerns about levels of student interest and engagement in science in school and student retention into tertiary study.
Cooper, Beverley, Cowie, Bronwen, Jones, Alister   +2 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

An arts and science information test [PDF]

, 1960
G. W. H. Leytham
openalex   +1 more source

Tracking down on 50-year History of Research about Information Management and Technology in Korea

Journal of Information Science Theory and Practice, 2013
Dept. of Domestic Information Information Service Center Korea Institute of Science and Technology Information
doaj   +1 more source