Das liest die LIBREAS, Nummer #1 (Sommer / Herbst 2017)
Redaktion LIBREAS
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In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen+17 more
wiley +1 more source
STABLE CONFIGURATION UNDER LOCAL MAJORITY TRANSFORMATIONS ON CELL SPACE : INFORMATION SCIENCE APPROACH TO BIOMATHEMATICS, V [PDF]
Masako Yamaguchi
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Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Review of "Visual Information Processing by William G. Chase" Center for Advanced Study in the Behavioral Sciences, Stanford, California, in SCIENCE. [PDF]
Ulric Neisser
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Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
Examining Experimental Raman Mode Behavior in Mono- and Bilayer 2H-TaSe2 via Density Functional Theory: Implications for Quantum Information Science. [PDF]
Chowdhury S+7 more
europepmc +1 more source
BUSCA DA INFORMAÇÃO EM MARKETING: A PERSPECTIVA DA CIÊNCIA DA INFORMAÇÃO
Based on marketing and information science perspectives the article reports the results of a survey into the innovation process inthree Brazilian industries.
Ricardo Rodrigues Barbosa+1 more
doaj
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source