Results 201 to 210 of about 24,852,160 (385)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The role of information science within the clinical translational science ecosystem. [PDF]

J Clin Transl Sci
Ragon B, Seymour A, Whipple EC, Surkis A, Haberstroh A, Muilenburg J, Rethlefsen ML, Aspinall EE, Deaver J, Dexter N, Barger R, Contaxis N, Glenn EJ, Hinton E, Kern B, Little M, Pickett K, Sevetson E, Tao D, von Isenburg M, Werner DA, Wheeler TR, Holmes K.   +22 more
europepmc   +1 more source

Book Review: Jerzy Muszyński: “Information Society: Political Science Drafts”, Adam Marszałek Publishing House, Toruń 2007, pp. 290 [PDF]

, 2006
Joanna Marszałek–Kawa
openalex   +1 more source

A cross-institutional analysis of data-related curricula in information science programmes: A focused look at the iSchools

Journal of information science, 2018
Virginia Ortiz-Repiso, J. Greenberg, Javier Calzada-Prado   +2 more
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Was ist Informationswissenschaft und wenn ja, wie viele? Ein Veranstaltungsbericht

Library Ideas, 2019
Carmen Krause
doaj   +1 more source

Stable organic radical qubits and their applications in quantum information science. [PDF]

Innovation (Camb)
Zhou A, Sun Z, Sun L.
europepmc   +1 more source

Applying interpretive phenomenological analysis to library and information science research on blended librarianship: A case study. [PDF]

Libr Inf Sci Res, 2020
Dabengwa IM, Raju J, Matingwina T.
europepmc   +1 more source

A Design Science Research Methodology for Information Systems Research

Journal of Management Information Systems, 2007
K. Peffers, T. Tuunanen, M. Rothenberger, S. Chatterjee   +3 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source