Results 31 to 40 of about 3,597,064 (317)
The structure of science information
Journal of Biomedical Informatics, 2002 The organization of information within science can be investigated in a principled way through analysis of science language. The restricted use of language in science enables description of the informational structure of science and of particular subfields, with strong similarities to structures in mathematics and programming languages.
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Research on Cross-media Science and Technology Information Data Retrieval [PDF]
arXiv, 2022 Since the era of big data, the Internet has been flooded with all kinds of information. Browsing information through the Internet has become an integral part of people's daily life. Unlike the news data and social data in the Internet, the cross-media technology information data has different characteristics. This data has become an important basis for
arxiv
Toward a New Science of Information
Information, 2011 Currently, a Science of Information does not exist. What we have is Information Science that grew out of Library and Documentation Science with the help of Computer Science.
Wolfgang Hofkirchner
doaj +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
New Times and New Challenges for Information Science: From Cellular Systems to Human Societies
Information, 2014 The extraordinary scientific-technical, economic, and social transformations related to the widespread use of computers and to the whole information and communication technologies have not been accompanied by the development of a scientific ...
Raquel del Moral +2 more
doaj +1 more source
Using Fisher information to track stability in multivariate systems [PDF]
Royal Society Open Science, 2016 With the current proliferation of data, the proficient use of statistical and mining techniques offer substantial benefits to capture useful information from any dataset.
Nasir Ahmad +3 more
doaj +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Current National Approach to Healthcare ICT Standardization: Focus on Progress in New Zealand [PDF]
Healthcare Informatics Research, 2015 ObjectivesMany countries try to efficiently deliver high quality healthcare services at lower and manageable costs where healthcare information and communication technologies (ICT) standardisation may play an important role.
Young-Taek Park, Koray Atalag
doaj +1 more source