Results 141 to 150 of about 899,494 (294)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

FROM E-LIBRARY SCIENCE TO LIBRARY INFORMATION SCIENCE

Proceedings of Altai State Academy of Culture and Arts, 2020
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Graduate education of library science in China: Current status and recommendations for improvement [PDF]

, 2009
More than twenty years ago, Wuhan University and Nanjing University offered library science (LS) graduate programs. Since then, LS graduate education has been grow-ing quickly in many aspects.
KE Ping, Ke Ping (ke2002@nankai.edu.cn), TANG Chengxiu, WANG Ping   +3 more
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Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Disciplinary Interflow of Library and Information Science in Taiwan

, 2010
本研究以「臺灣人文學引文索引資料庫」收錄之1996-2002圖書資訊學期刊論文為研究對象，探討台灣近年之圖書資訊學跨學科研究的特性。研究結果顯示，圖書資訊學研究者最常與「社會科學」及「工程技術」類的研究者進行合作研究，從事「圖書資訊技術」和「讀者服務」的研究者，比較常與其他學科的研究者進行合作研究。至於引用之行為，圖書資訊學研究者最常引用「社會科學」、「攻城技術」和「歷史」類的文獻資料，其中又以論文出版前五至十年之中文圖書為主。跨學科引用指數顯示「行政與管理」這類的研究主題跨學科引用程度是最高的 ...
Chen, Kuang-hua; Liang, Chiung-fang, 陳光華; 梁瓊方   +1 more
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Political Reformation and its Impact on Library And Information Science Education And Practice: A Case Study Of Indonesia During And Post-President-Soeharto Administration [PDF]

, 2006
The author discusses library and information science education before and after 1998, the year President Soeharto stepped down. Before 1998, the government centralized policy making.
L Sulistyo-Basuki, Sulistyo-Basuki, L., Sulistyo-Basuki, L   +2 more
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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Foundations of Library and Information Science

, 2010
To meet the evolving needs of a dynamic profession, the new edition of Richard Rubin s best selling text has been streamlined using feedback from faculty, students, and an outstanding Editorial Board: Kendra Albright, SLIS, University of South Carolina ...
Rubin, Richard E.
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