Results 61 to 70 of about 4,838,803 (356)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Ciência da informação e educação/Information science and education

ETD: Educação Temática Digital, 2007
Apresenta a área Ciência da Informação e seus objetos de estudo no mesmo movimento em que esses objetos de estudo são pensados na interrelação com a Educação, tornando assim a questão da autoria, do uso de periódicos educacionais e o funcionamento dos ...
Solange Puntel Mostafa
doaj  

Library and information science publishing : global open access [PDF]

, 2005
Brief article describing E-LIS, an open access repository for library and information science material in a range of formats and languages. E-LIS was set up in 2003 with initial funding from the Spanish Ministry of Education, Culture and Sports, in line ...
Brown, Kristina, McCulloch, Emma
core   +1 more source

International data curation education action (IDEA) working group: a report from the second workshop of IDEA [PDF]

, 2009
The second workshop of the International Data curation Education (IDEA) Working Group was held December 5, 2008, in Edinburgh, Scotland, following the 4th International Digital Curation Conference.
Davidson, J., Hank, C.
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Aqua: AIRS, AMSU, HSB, AMSR-E, CERES, MODIS [PDF]

, 2002
This brochure provides an overview of the Aqua spacecraft, instruments, science, and data products Aqua, Latin for water, is a NASA Earth Science satellite mission named for the large amount of information that the mission is collecting about the Earth's

core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Journal “Topics in Early Childhood Special Education”: assessment of the periodical and articles

Revista Educação Especial, 2008
Journals have the purpose of dissemination and communication of scientific knowledge. As a vehicle to the dissemination of scientific productions, it is necessary the periodical assessment to evaluate the quality of research: accuracy, reliability and ...
Paulo Celso Pereira, Karyne de Souza Augusto Rios   +1 more
doaj   +1 more source

Connecting teachers and students with science and scientists: The science learning hub [PDF]

, 2010
National and international data is raising concerns about levels of student interest and engagement in science in school and student retention into tertiary study.
Cooper, Beverley, Cowie, Bronwen, Jones, Alister   +2 more
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