Results 51 to 60 of about 281,646 (307)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Modeling the Information-Seeking Behavior of Social Scientists: Ellis's Study Revisited [PDF]
, 2003 This paper revises David Ellis's information-seeking behavior model of social scientists, which includes six generic features: starting, chaining, browsing, differentiating, monitoring, and extracting.
Meho, Lokman I., Tibbo, Helen R.
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Gender differences in information behavior during the Covid-19 health crisis in Spain
JLIS.it, 2021 The Covid-19 pandemic has produced numerous deaths throughout the planet, although in general it has been deadlier in older people, in people with previous conditions and in males.
Michela Montesi
doaj +6 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Information-seeking behaviour of physicists and astronomers [PDF]
, 2008 Purpose – The study examines two aspects of information seeking behaviour of physicists and astronomers including methods applied for keeping up-to-date and methods used for finding articles. The relationship between academic status and research field of
Jamali, Hamid R., Nicholas, David
core
Internet Information and Communication Behavior during a Political Moment: The Iraq War, March 2003 [PDF]
, 2008 This article explores the Internet as a resource for political information and communication in March 2003, when American troops were first sent to Iraq, offering us a unique setting of political context, information use, and technology.
Alice Robbin +3 more
core +1 more source
Information Avoidance: a Systematic Review
Iranian Journal of Information Processing & Management, 2021 The aim of this study is to understand the concept of information avoidance in terms of origin, effective factors, behaviors, areas of the previous studies, and research gaps.
Mahsa Torabi, Mahdieh Mirzabeigi
doaj
Information Acquisition and Avoiding Behavior among Parents of Children with Phenylketonuria: A Cross-Sectional Study [PDF]
International Journal of Information Science and ManagementInformation has a crucial role in the management of Phenylketonuria (PKU). This study aimed to investigate information acquisition and avoidance behavior among parents of children with PKU and determine the associated factors. This cross-sectional survey
Leila Pirmohammadi Pourfard +4 more
doaj +1 more source