Results 61 to 70 of about 1,408,696 (299)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Customer value co-creation behavior : scale development and validation [PDF]
, 2013 This investigation reports a series of four studies leading to the development and validation of a customer value co-creation behavior scale. The scale comprises two dimensions: customer participation behavior and customer citizenship behavior, with each
Gong, Taeshik, Yi, Youjae
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Information Avoidance: a Systematic Review
Iranian Journal of Information Processing & Management, 2021 The aim of this study is to understand the concept of information avoidance in terms of origin, effective factors, behaviors, areas of the previous studies, and research gaps.
Mahsa Torabi, Mahdieh Mirzabeigi
doaj
Information Acquisition and Avoiding Behavior among Parents of Children with Phenylketonuria: A Cross-Sectional Study [PDF]
International Journal of Information Science and ManagementInformation has a crucial role in the management of Phenylketonuria (PKU). This study aimed to investigate information acquisition and avoidance behavior among parents of children with PKU and determine the associated factors. This cross-sectional survey
Leila Pirmohammadi Pourfard +4 more
doaj +1 more source
Gender differences in information behavior during the Covid-19 health crisis in Spain
JLIS.it, 2021 The Covid-19 pandemic has produced numerous deaths throughout the planet, although in general it has been deadlier in older people, in people with previous conditions and in males.
Michela Montesi
doaj +6 more sources
The relationship of (perceived) epistemic cognition to interaction with resources on the internet [PDF]
, 2017 Information seeking and processing are key literacy practices. However, they are activities that students, across a range of ages, struggle with. These information seeking processes can be viewed through the lens of epistemic cognition: beliefs regarding
Knight, Simon +5 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source