Results 61 to 70 of about 281,646 (307)
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Physicists' information behavior: a qualitative study of users [PDF]
The work analyzes information seeking behavior of students who are in the process of getting a PhD in Physics or who have recently done so. The analysis was made within the sense making approach which is centered in the user.
Gómez, Nancy-Diana
core
Investigating the information-seeking behaviour of academic lawyers: from Ellis’s model to design
Information-seeking is important for lawyers, who have access to many dedicated electronic resources. However there is considerable scope for improving the design of these resources to better support information-seeking. One way of informing design is to
Cox, Anna L. +6 more
core +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Information Seeking Behavior and Needs of Women Parliamentarians of Pakistan: A Case Study [PDF]
This study probes into the information needs and seeking behavior of women parliamentarians in the 12th National Assembly of Pakistan during 2002 through 2007.
Naqvi, Syeda Bushra Nazli +2 more
core
What is the information Seeking and Behavior of Information Seeking?
Whatever population and using computerized systems in home, Official and receptive dimensions is increasing, whatever digital data is increasing and then searching of users is increasing too. Surely users have problems, Like: Selecting information sources that dont answer to informational needs, disability to specification available facilities in ...
openaire +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Research within Library and Information Sciences bespeaks of the significant tendency of (expert and non-expert) users towards informal information sources.
Reza Mokhtarpour
doaj
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Humans do different behaviors to meet their needs constantly. These behaviors are different and each of them constitute subject of disciplines such as psychology, sociology, management, art, knowledge and information science, and some specialized sub ...
Ali Akbari +2 more
doaj

