Results 71 to 80 of about 20,784,264 (262)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Peran Media Sosial Sebagai Promosi Pemanfaatan Jasa Informasi di Perpustakaan Universitas Islam Negeri Imam Bonjol Padang

open access: yesJurnal Pustaka Ilmiah
Leaders are responsible for the organization's progress based on the vision, mission, and goals of the organization they lead. This paper analyzes the leadership style of female library heads using the theory of Behavioral Mahakumaran. A leader will be a
Shinta Nofita Sari, Nurul Salma
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Other title: Long-Term Care Survey Update

open access: yes, 2018
application/pdf; "January 29, 2018."; Presentation before the Kansas Legislature, House Health and Human Services Committee, by the Kansas Department for Aging and Disability Services.; This same presentation was given before the Kansas Legislature ...
Kansas. Department for Aging and Disability Services.
core  

Education: 8. Music Education and Research Through Infodocumentary Services

open access: yesReview of Artistic Education, 2018
In the paper are reflected some moments from the evolution of musical education and research at Alecu Russo Balti State University, suitable for the info-documentary services system, connection and relationship of librarians with teachers, students and ...
Ţurcan Elena, Harconiţa Elena
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Other title: Social and Rehabilitation Services Information Technology Update; Other title: Information Technology Update

open access: yes, 2003
Cover title.; "August 21, 2003."; Testimony before the Kansas Legislature, Joint Committee on Information Technology by Steve Patterson, Chief Information Officer of the Operations Division/Information Technology Services within the Kansas ...
Patterson, Steve.
core  

The Personalization of Information Services [PDF]

open access: yes, 2003
The Internet removes the temporal and spatial barriers and enables information professionals to offer information services to remote users 24 hours a day and seven days a week.
Tonta, Yaşar
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy