Results 81 to 90 of about 15,342,768 (327)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The role of higher education policy in planning information governance at UIN Maulana Malik Ibrahim

Berkala Ilmu Perpustakaan dan Informasi
Introduction. This study aims to explore the role of higher education policy in planning information governance at the Islamic university, UIN Maulana Malik Ibrahim. Data Collection Methods.
Nita Siti Mudawamah, Annisa Fajriyah, Ganis Chandra Puspitadewi, Firman Jati Pamungkas, Aulia Mi'rojtin Firdaus   +4 more
doaj   +1 more source

An investigation on the forms of information sources and services utilised among rural dwellers from public libraries in the North-West zone of Nigeria

South African Journal of Information Management, 2019
Background: Rural dwellers need timely, accurate, pertinent and reliable information for sustainable rural development. However, in Nigeria it is estimated that over 70% of people are living in rural areas who are mainly non-literate people who cannot ...
Badamasi B. Mohammed, Francis Garaba
doaj   +1 more source

Marketing of information products and services in public libraries in South West, Nigeria [PDF]

, 2018
Jacob Oloruntoba Kutu, Olabode Olajide
openalex   +1 more source

Making market information services work better for the poor in Uganda

, 2014
To assist smallholder farmer commercialisation, a new generation of low-cost market information services (MIS) has been developed in Uganda. These MIS services take advantage of new information and communication technologies (ICT).
S. Ferris, P. Engoru, E. Kaganzi
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Clinical and Information Services Needed by Telemental Health Providers. [PDF]

Telemed J E Health, 2023
Paige SR, Ong T, Wilczewski H, Barrera JF, Welch BM, Bunnell BE.   +5 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Exploring the training of chinese medical staff oriented to the need for clinical drug information services: from the perspective of drug information patients obtained and need. [PDF]

BMC Med Educ, 2023
Huang R, Huang Y, Liu J, Chen L.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source