Results 71 to 80 of about 17,651,615 (259)
Drug target, class level, and PathFX pathway information share utility for machine learning prediction of common drug-induced side effects. [PDF]
Front Drug Saf Regul, 2023 Liu HJ, Wilson JL.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Re-measuring labor's share [PDF]
Measuring labor's share of an economy's aggregate income seems straightforward,at least in principle. Count up wage and salary income, along with the value of benefitsprovided to employees, and divide it by total income.
Hernando Zuleta, Andrew T. Young
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Kansas Information Technology Architecture
, 2009 Version 11.2; application/pdf; Cover title.; "12/28/2009."; "This Architecture provided to the State of Kansas by the Kansas Technical Architecture Review Board (KTARB), presented to and approved by the Information Technology Executive ...
Kansas. Information Technology Office.
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Share repurchase regulations: do firms play by the rules? [PDF]
Open market share repurchases are strictly regulated to prevent companies from profiting from insider information. We examine compliance with these rules in France, where the mandatory disclosure of share repurchases provides detailed information on ...
Jacques Hamon, Edith Ginglinger
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Open market share reacquisitions, surplus cash, and agency problems [PDF]
, 2004 This paper investigates the role that excess cash plays in explaining actual open market share reacquisitions and examines the impact of agency problems on the payout decision.
Young, S E, Oswald, D
core +3 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 2013 Version 5.2.; application/pdf; "12.9.2013."; "The Kansas Bureau of Investigation (KBI) and the Kansas Highway Patrol (KHP) share the administrative and operational responsibilities for core KCJIS functions."--Page [4 of 259].; Includes the "Criminal ...
Kansas Criminal Justice Information System.
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