Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The decline of the U.S. labor share [PDF]
Over the past quarter century, labor’s share of income in the United States has trended downward, reaching its lowest level in the postwar period after the Great Recession.
Sahin, Aysegul +5 more
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
The Dividend and Share Repurchase Policies of Canadian Firms: Empirical Evidence based on New Research Design [PDF]
We empirically investigate dividend and share repurchase policies of Canadian firms. We use several logit regression analyses to test the structure and determinants of the dividend and share repurchase choice.
Dijk, R. van, Jong, A. de, Veld, C.H.
core
How To Share Your Driving Licence Information?
Follow this guide to provide detail on your driving entitlements and any endorsements such as when applying for a job or hiring a vehicle. Step 1 - Visit the online Portal.
Sophia Jones
core +2 more sources
Market reaction to tender and private offers on the JSE
Investors can benefit when incorporating the information-signalling effect of share repurchases in their investment strategies. Previous South African studies on open market share repurchases confirmed the globally observed signalling-effect, but found ...
N. Wesson, C. Muller, M. Ward
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Health Information Sources Within Low Income Black Communities: A Families SHARE Study
Background Access to credible health information is critical for health literacy and informed health behaviors. Although digital platforms are widely used, limited technology access and lower eHealth literacy may constrain online health information ...
Kristen Judy +4 more
doaj +1 more source
Willingness to share information on social media: a systematic literature review (2020–2024)
IntroductionThe rapid advancement of Web 2.0 technologies, accelerated by the COVID-19 pandemic, has fundamentally transformed information sharing behaviors on social media.
Yingying Cai +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

