Results 101 to 110 of about 993,913 (308)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The Economic Incentives for Sharing Security Information [PDF]

Given that Information Technology (IT) security has emerged as an important issue in the last few years, the subject of security information sharing among firms, as a tool to minimize security breaches, has gained the interest of practitioners and ...
Anindya Ghose, Esther Gal-Or
core  

Oakland Seaport, CA: Industry and Public Sector Cooperation for Information Sharing [PDF]

, 2013
(MIST Oakland)Multimodal Information Sharing Team (MIST)The Multimodal Information Sharing Team (MIST) is an evolution of the Maritime Information Sharing Taskforce that has been conducting workshops in domestic ports since 2008.
Englehorn, Lyla, Hocevar, Susan Page, Walsh, Wendy, Salem, Anita   +3 more
core  

Real-world oriented information sharing using social networks

, 2005
While users disseminate various information in the open and widely distributed environment of the Semantic Web, determination of who shares access to particular information is at the center of looming privacy concerns.
Tatsuhiko Sugiyama, Matsuo, Yutaka, Mori, Junichiro, Yutaka Matsuo, Junichiro Mori, Sugiyama, Tatsuhiko   +5 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Role and Effects of Credit Information Sharing [PDF]

Information sharing about borrowers’ characteristics and their indebtedness can have important effects on credit markets activity. First, it improves the banks’ knowledge of applicants’ characteristics and permits a more accurate prediction of their ...
Marco Pagano, Tullio Jappelli
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Exploring the Effects of Information Sharing on Organizational Dependence

, 2012
[[abstract]]Researches in marketing suggest that delivering specific services to foster customer dependence on the relationship is a strategic imperative for retaining profitable buyer firms.
Tai, Y.M., Lin, S.C., 楊書成, Ku, Y.C.   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Health Assessment of Terrestrial Ecosystems in China Based on the Adaptive Indicator Reduction Method

Remote Sensing
Assessing terrestrial ecosystem health in China is crucial for guiding national economic strategies and ecological conservation. To address the lack of a unified national evaluation system, this study integrates the Pressure–State–Response (PSR) and ...
Xiaoqin Wang, Dongyue Wang, Jianhui Chen, Mengjing Lin   +3 more
doaj   +1 more source