Results 111 to 120 of about 993,913 (308)

Country Creditor Rights, Information Sharing, and Commercial Banks’ Profitability [PDF]

The authors analyze commercial banks’ profitability (return on equity, ROE) at different levels of creditor rights and an aggregate score of information sharing in terms of credit bureaus. After controlling for bank size and some macroeconomic variables,
María T. Tascón, Borja Amor-Tapia, José L. Fanluj   +2 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Information sharing - Benefits

Journal of Computer Science and Technology, 2012
Government Information Sharing (GIS) allows information exchange and integration between different government departments, agencies, as well as between public and private institutions. Sharing information enables enhanced efficiency -avoiding duplication of processes updating the same data; better quality of processes and services- removing inconsistent
Mendes Calo,Karla, Cenci, Karina, Fillottrani, Pablo Rubén, Estevez, Elsa   +3 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Building Type Classification Using CNN-Transformer Cross-Encoder Adaptive Learning From Very High Resolution Satellite Images

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Building type information indicates the functional properties of buildings and plays a crucial role in smart city development and urban socioeconomic activities.
Shaofeng Zhang, Mengmeng Li, Wufan Zhao, Xiaoqin Wang, Qunyong Wu   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

ICA-ASIFT-Based Multi-Temporal Matching of High-Resolution Remote Sensing Urban Images

Cybernetics and Information Technologies, 2016
While SIFT (Scale Invariant Feature Transform) features are used to match High-Resolution (HR) remote sensing urban images captured at different phases with large scale and view variations, feature points are few and the matching accuracy is low ...
Huang Fenghua, Mao Zhengyuan, Shi Wenzao
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The Assessment of Industrial Agglomeration in China Based on NPP-VIIRS Nighttime Light Imagery and POI Data

Remote Sensing
Industrial agglomeration, as a typical aspect of industrial structures, significantly influences policy development, economic growth, and regional employment.
Zuoqi Chen, Wenxiang Xu, Zhiyuan Zhao
doaj   +1 more source