Results 101 to 110 of about 20,813,728 (374)

Attitudes towards risk-stratified breast cancer screening in Denmark – a qualitative study

open access: yesBMC Cancer
Background Today the prerequisites exist to initiate risk-stratified screening according to a woman’s individual risk of breast cancer as opposed to existing one-size-fits-all age-based programmes.
Ann-Britt Kvernrød   +4 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Information society before information society

open access: yes, 2008
The discourse on “the information society” developed until the 70’s as one of the prevailing discourse in our society; with promises to link information technology and free market with economic growth and human progress. This eventually became something like the official ideology of the European Union as demonstrated by the famous Lisbon strategy to ...
openaire   +1 more source

The Role of Local Governments in Information Society [PDF]

open access: yes
With the growing accessibility of electronic local governmental services local governments are facing new challenges both from the point of view of the organisation of duties and of their client services.
Anna Francsovics, Attila Pál
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Information Technology and Sustainability in the Information Society

open access: yesInternational Journal of Communication, 2017
The sustainability concept has developed in a policy context. Its main relevance has been in policy forums such as the United Nations Conference on Environment and Development and the United Nations Conference on Sustainable Development. In the realm of
Christian Fuchs
doaj   +2 more sources

Revista Iberoamericana de Tecnologías del Aprendizaje (IEEE-RITA) (Latin-American Learning Technologies Journal) Society Information [PDF]

open access: bronze, 2021
Martn Llamas Nistal   +59 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Statistical Computing in Information Society

open access: yesFolia Oeconomica Stetinensia, 2015
In the presence of massive data coming with high heterogeneity we need to change our statistical thinking and statistical education in order to adapt both - classical statistics and software developments that address new challenges.
Domański Czesław, Jędrzejczak Alina
doaj   +1 more source

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