Results 61 to 70 of about 33,986,606 (242)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Towards the information society
Theory, Methodology, Practice, 2004 A new social class of the XXI century, the information society, is emerging as a result of the convergence of telecommunication, information technology and electronic media called infocommunication technologies (ICT) and it is based on the developing ...
Sándor Illés
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Volume 11 - 1980: KEEPING CURRENT WITH GEOSCIENCE INFORMATION - Proceedings of the 15th Meeting of the Geoscience Information Society [PDF]
, 1980 Proceedings of the 15th Meeting of the Geoscience Information Society held November 16-20, 1980 in Atlanta ...
Geoscience Information Society
core +1 more source
Impact of the development of information society on healthcare efficiency: Empirical evidence from 31 Chinese provinces. [PDF]
Digit Health, 2023 Hu Y, Wang Y, Lu S, Li Y.
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Participatory methods for information society
Filozofia Publiczna i Edukacja Demokratyczna, 2016 The paper provides introductory remarks to the special issue of Public Philosophy and Democratic Education dedicated to the role of participatory methods in contemporary informational society.
Mateusz Bonecki, Anna Malitowska
doaj +1 more source