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Space law information system design, phase 2 [PDF]
Design alternatives were defined for the implementation of a Space Law Information System for the Office of the General Counsel, NASA. A thesaurus of space law terms was developed and a selected document sample indexed on the basis of that thesaurus ...
Morenoff, J. +2 more
core +1 more source
Deep Space Network information system architecture study [PDF]
, 1992 The purpose of this article is to describe an architecture for the Deep Space Network (DSN) information system in the years 2000-2010 and to provide guidelines for its evolution during the 1990s.
Atkinson, D. J. +9 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Patients Are Knowledge Workers in the Clinical Information Space. [PDF]
Appl Clin Inform, 2021 Papautsky EL, Patterson ES.
europepmc +1 more source
Functional representation of vision within the mind: A visual consciousness model based in 3D default space [PDF]
, 2015 The human eyes and brain, which have finite boundaries, create a ‘‘virtual’’ space within our central nervous system that interprets and perceives a space that appears boundless and infinite.
Barnes, Vernon A. +2 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Information management in an integrated space telerobot [PDF]
The in-orbit operations, like space structures inspection, servicing and repairing, is expected to be one of the most significant technological area for application and development of Robotics and Automation in Space Station environment.
Dipippo, S. +2 more
core +1 more source
Building Cyberspace. Information, Place and Policy [PDF]
, 1998 Information and place have always been linked. From prehistoric forest and hydraulic expire to canal network and the networked knowledge economy, the space of flows gives rise to the way human beings perceive the world as well as to the objects they ...
Friedman, Ken
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source