Results 121 to 130 of about 7,221,706 (293)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Design of an Integrated Space-Based Information Support Digital Infrastructure
IEEE AccessTo address systemic challenges including decentralized construction, functional redundancy, and network heterogeneity in space-based information systems in the New Space Age, For the first time, this study formulates a unified, modular, and service ...
Pengbo Li, Gang Wan, Zhongmin Pei
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Complex & Intelligent SystemsRemote sensing image pairs of different time phases have complex and changeable semantic contents, and traditional convolutional registration methods are challenging in modeling subtle local changes and global large-scale deformation differences in ...
Xie Zhuli +3 more
doaj +1 more source
ВЗАИМОСВЯЗЬ ИНФОРМАЦИОННОГО ПРОСТРАНСТВА И ВЫБОРА МОДЕЛИ ОТКЛОНЯЮЩЕГОСЯ ПОВЕДЕНИЯ ШКОЛЬНИКАМИ
Sovremennye Issledovaniâ Socialʹnyh Problem, 2015 В статье представлено понимание проблемы экспансивно развивающегося информационного пространства как фактора влияющего на социализацию школьников. Дается характеристика современного информационного пространства, анализируются подходы к его изучению ...
Denis Alexandrovich Davydov +2 more
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Remote SensingSemantic change detection has become a key technology for monitoring the evolution of land cover and land use categories at the semantic level. However, existing methods often lack effective information interaction and fail to capture changes at multiple
Zhuli Xie +4 more
doaj +1 more source
Architecture and the Spaces of Information [PDF]
Architecture and Culture, 2016 Blacksell, R., Walker, S.
openaire +3 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source