Results 231 to 240 of about 4,309,068 (299)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Large Language Models for Summarizing Advance Care Planning Information From Goals of Care Notes in the EHR. [PDF]

Learn Health Syst
Ekbote N, Akhondzadeh M, Graham R, Bell J, Glasser D, El-Kareh R, Chua A, Boussina A, Tai-Seale A, Poursoltan L, Singh K, Agnihotri P, Tai-Seale M.   +12 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A multi-task deep learning framework for simultaneous prediction of microsatellite instability and tumor mutational burden in gastric cancer from histopathological images. [PDF]

Front Oncol
Chang Y, Chang H, Lv Y, Xi S, Yang J, Wang B, Zheng X, Xie Y.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Information-Seeking Patterns and Communication Preferences Among Japanese Survivors With Cancer: Cross-Sectional Analysis. [PDF]

JMIR Cancer
Hirayama M, Kasai D, Tabei KI.
europepmc   +1 more source

Digital Health Engagement Regarding Lumbar Disc Herniation in Terms of Exercise Adherence: Integrating Variable-Centered and Person-Centered Perspectives. [PDF]

Patient Prefer Adherence
Xu X, Qu Q, Chen T, Shao X.
europepmc   +1 more source

Completeness of the COVID-19 vaccination schedule and associated factors among persons experiencing homelessness in Brazil: a national cross-sectional study. [PDF]

BMJ Open
Soares Tenorio de Araújo J, Berra TZ, Tártaro AF, Rosa RJ, Tavares RBV, Alves YM, Pelodan MEP, Moura HSD, Ferezin LP, Ramos ACV, do Nascimento MC, Lima de Freitas G, Arcêncio RA.   +12 more
europepmc   +1 more source

Correction: The effect of online hygiene information expression on customers' institutional and cognitive trust in tourist accommodation. [PDF]

Front Public Health
Zhang B, Li Y, Fang X, Huang W, Meng Q.
europepmc   +1 more source