Results 31 to 40 of about 57,000 (292)

eHealth: Towards a Healthcare Service-Oriented Boundary-Less Infrastructure [PDF]

Applied Medical Informatics, 2010
The current paper presents several interoperability features applied to a local distributed information system, CardioNET, meant to improve quality of healthcare services, through the use of the latest medical and IT&C technologies.
Cristian LELUTIU, Lorand KRUCZ, Nicolae TODOR, Gavril SAPLACAN, Gheorghe SEBESTYEN, Mircea RUSU   +5 more
doaj  

A Virtual-Ring-Based Data Storage and Retrieval Scheme in Wireless Sensor Networks

International Journal of Distributed Sensor Networks, 2012
In-network data storage and retrieval is one of the most important problems in wireless sensor networks. Many schemes have been proposed to solve this problem. However, most of them do not take the frequencies of event and query into consideration.
Xingpo Ma, Jianliang Gao, Weiping Wang, Jianxin Wang   +3 more
doaj   +1 more source

Recall and Precision of Persian Databases for Retrieval of Scholarly Information in the Field of Occupational Injuries

مدیریت اطلاعات سلامت, 2020
Introduction: Use of databases for accessing electronic documents has increased the necessity of reviewing the performance and coverage of these databases. The aim of this study was to assess the recall and precision of Persian databases for retrieval of
Ali Bahari, Homayoun Sadeghi-Bazargani, Fahimeh Bakhtiari   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Clinical Data Element Ontology for Unified Indexing and Retrieval of Data Elements across Multiple Metadata Registries [PDF]

Healthcare Informatics Research, 2014
ObjectivesClassification of data elements (DEs), which is used in clinical documents is challenging, even in across ISO/IEC 11179 compliant clinical metadata registries (MDRs) due to no existence of reliable standard for identifying DEs.
Senator Jeong, Hye Hyeon Kim, Yu Rang Park, Ju Han Kim   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

بازيابی تصاوير: کاربرد در پزشکی

مدیریت اطلاعات سلامت, 2013
هدف هر نظام بازيابی اطلاعات پزشکی، ارائه به‌موقع اطلاعات مرتبط در زمان مناسب به کاربر مناسب است. تصاوير به‌عنوان شکلی از مدارک که می‌توانند حجم قابل توجهی از اطلاعات را منتقل کنند از اهميت خاصی برخوردارند.
Maryam Okhovati, Reza Akbarnejad, Kambiz Bahaadinbeigy   +2 more
doaj  

Search Personalization Based on Social-Network-Based Interestedness Measures

IEEE Access, 2019
Personalized search methods try to tailor the search results to the user's needs and preferences. A popular source of information for personalization is social networks of users.
Shayan A. Tabrizi, Azadeh Shakery, Mohammad Ali Tavallaei, Masoud Asadpour   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source