Results 41 to 50 of about 77,832 (293)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A Virtual-Ring-Based Data Storage and Retrieval Scheme in Wireless Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2012
In-network data storage and retrieval is one of the most important problems in wireless sensor networks. Many schemes have been proposed to solve this problem. However, most of them do not take the frequencies of event and query into consideration.
Xingpo Ma   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Clinical Data Element Ontology for Unified Indexing and Retrieval of Data Elements across Multiple Metadata Registries [PDF]

open access: yesHealthcare Informatics Research, 2014
ObjectivesClassification of data elements (DEs), which is used in clinical documents is challenging, even in across ISO/IEC 11179 compliant clinical metadata registries (MDRs) due to no existence of reliable standard for identifying DEs.
Senator Jeong   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

بازيابی تصاوير: کاربرد در پزشکی

open access: yesمدیریت اطلاعات سلامت, 2013
هدف هر نظام بازيابی اطلاعات پزشکی، ارائه به‌موقع اطلاعات مرتبط در زمان مناسب به کاربر مناسب است. تصاوير به‌عنوان شکلی از مدارک که می‌توانند حجم قابل توجهی از اطلاعات را منتقل کنند از اهميت خاصی برخوردارند.
Maryam Okhovati   +2 more
doaj  

Search Personalization Based on Social-Network-Based Interestedness Measures

open access: yesIEEE Access, 2019
Personalized search methods try to tailor the search results to the user's needs and preferences. A popular source of information for personalization is social networks of users.
Shayan A. Tabrizi   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

On the Storage Cost of Private Information Retrieval [PDF]

open access: yes2020 IEEE International Symposium on Information Theory (ISIT), 2020
17 pages, 3 ...
openaire   +4 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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