Results 61 to 70 of about 68,085 (316)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

What every urologist should know about surgical trials Part II: What are the results and should I apply them to patient care?

open access: yesIndian Journal of Urology, 2008
Surgical interventions have inherent benefits and associated risks. Before implementing a new therapy, we should ascertain the benefits and risks of the therapy, and assure ourselves that the resources consumed in the intervention will not be exorbitant.
Sohail Bajammal   +2 more
doaj   +1 more source

Use of IR_Framework in the Teaching of Information Retrieval [PDF]

open access: yes, 2000
This paper discusses recent work on the development of an application based on IR_Framework, an extensible class library for information retrieval currently under development at the University of Huddersfield.
Braekevelt, Patrick, Wade, Steve
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Smart Search Engine For Information Retrieval [PDF]

open access: yes, 2009
This project addresses the main research problem in information retrieval and semantic search. It proposes the smart search theory as new theory based on hypothesis that semantic meanings of a document can be described by a set of keywords.
SUN, LEILEI
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

What every urologist should know about surgical trials Part I: Are the results valid?

open access: yesIndian Journal of Urology, 2008
Surgical interventions have inherent benefits and associated risks. Before implementing a new therapy, we should ascertain the benefits and risks of the therapy, and assure ourselves that the resources consumed in the intervention will not be exorbitant.
Sohail Bajammal   +2 more
doaj   +1 more source

The derivation of a behavioural model for information retrieval system design. [PDF]

open access: yes, 1987
This study outlines the derivation of a behavioural model intended to underpin thinking on questions concerning the design of information retrieval systems for academic social scientists.
Ellis, David, Ellis, D
core  

Adaptive image retrieval using a graph model for semantic feature integration [PDF]

open access: yes, 2006
The variety of features available to represent multimedia data constitutes a rich pool of information. However, the plethora of data poses a challenge in terms of feature selection and integration for effective retrieval.
Urban, J.   +4 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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