Results 61 to 70 of about 77,832 (293)
What every urologist should know about surgical trials Part I: Are the results valid?
Indian Journal of Urology, 2008 Surgical interventions have inherent benefits and associated risks. Before implementing a new therapy, we should ascertain the benefits and risks of the therapy, and assure ourselves that the resources consumed in the intervention will not be exorbitant.
Sohail Bajammal +2 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Venturing into the labyrinth: the information retrieval challenge of human digital memories [PDF]
, 2007 Advances in digital capture and storage technologies mean that it is now possible to capture and store one’s entire life experiences in a Human Digital Memory (HDM).
Kelly, Liadh, Jones, Gareth J.F.
core +2 more sources
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Information Storage and Retrieval Systems [PDF]
, 1983 This thesis describes the implementation of a general purpose personal information storage and retrieval system. Chapter one contains an introduction to information storage and retrieval.
Creech, Teresa Adams
core
Context and linking in retrieval from personal digital archives [PDF]
, 2008 Advances in digital capture and storage technologies mean that it is now possible to capture and store one’s entire life experiences in personal digital archives.
Kelly, Liadh, Liadh Kelly
core +2 more sources
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
FEBS Open Bio, EarlyView.Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
New Horizons for a Data-Driven Economy
, 2016 Information Storage and Retrieval; Innovation/Technology Management; Computer Applications; Computers and Society; Big ...
core +1 more source