Results 151 to 160 of about 10,604,090 (302)
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
A bull's eye view of management and engineering information systems [PDF]
, 1964 Anthony G. Oettinger
openalex +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
A public philosophy for real time information systems [PDF]
, 1968 Harold Sackman
openalex +1 more source
The Work System Method for Understanding Information Systems and Information Systems Research
Communications of the Association for Information Systems, 2002 The work system method is a broadly applicable set of ideas that use the concept of “work system” as the focal point for understanding, analyzing, and improving systems in organizations, whether or not IT is involved. The premises underlying this method may be controversial in the IS community because they imply that the traditional jargon and concerns
openaire +4 more sources
Development of a new method for creating the working surface of a large-sized transformable reflector [PDF]
Космические аппараты и технологииIn the design of large-sized umbrella-type reflectors, a form-building structure is used to create the working surface. The form-building structure in the open position is a system of tensioned threads.
P. V. Belousov +3 more
doaj
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Advanced information processing system: Local system services [PDF]
The Advanced Information Processing System (AIPS) is a multi-computer architecture composed of hardware and software building blocks that can be configured to meet a broad range of application requirements. The hardware building blocks are fault-tolerant,
Alger, Linda +3 more
core +1 more source