Results 231 to 240 of about 15,399,652 (281)

Information Systems Development with Pair Programming: An Academic Quasi-Experiment

, 2016
Eduardo Fernandes, Fischer Ferreira, João Antônio Netto, Eduardo Figueiredo   +3 more
openalex   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Health information system in primary health care units of the Central Zone, Tigray, Northern Ethiopia. [PDF]

BMC Med Inform Decis Mak
Gebretsadik LG, Belachew AB, Gebrekidan GB, Bayray A, Lemlem A, Dangew LB, Abebe HT.   +6 more
europepmc   +1 more source

Analisis dan Perancangan Geographic Information System pada Pelacakan Lokasi Kurir Secara Real Time

, 2018
Muhamad Anbiya Nur Islam, Much Aziz Muslim, Hendi Susanto   +2 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A heuristic evaluation of a pharmacy surveillance information system. [PDF]

BMC Med Inform Decis Mak
Abbasi R, Farzandipour M, Rahimi H, Gong Y, Nabovati E.   +4 more
europepmc   +1 more source

Study on Intelligent Logistics Management Information System Based onIOT and Cloud Computation in Big Data Era

, 2015
Yajun Guo, QU Jin-li
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Utilisation of data and factors affecting the performance of the Health Management Information System (HMIS). The case of six Synods of Livingstonia health facilities in Malawi. [PDF]

Arch Public Health
Salangwa C, Munthali R, Mfune L, Nyirenda VK.   +3 more
europepmc   +1 more source