Results 71 to 80 of about 33,517,941 (337)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Protecting information in systems of systems [PDF]

, 2011
Systems of Systems (SoS) are dynamic, distributed coalitions of autonomous and heterogeneous systems that collaborate to achieve a common goal. While o¿ering several advantages in terms of scalability and ¿exibility, the SoS paradigm has a strong impact on system interoperability and on the security requirements of collaborating parties.
Daniel Trivellato, Sandro Etalle, Nicola Zannone   +2 more
openaire   +3 more sources

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

DEVELOPMENT OF SALES APPLICATION OF PREPAID ELECTRICITY VOUCHER BASED ON ANFROID PLATFORM USING QUICK RESPONSE CODE (QR CODE)

Jurnal Informatika, 2017
Perusahaan Listrik Negara (PLN) has implemented a smart electricity system or prepaid electricity. The customers pay the electricity voucher first before use the electricity.
Ricky Akbar, Husnil Kamil
doaj   +1 more source

Computer & Network Equipment Management System (CNEMAS) Application Measurement

International Journal of Informatics, Information System and Computer Engineering, 2020
ABC is one of the state-owned enterprises in Indonesia. PT. ABC has policy to give some equipment for employees to rent. Application use to control all equipment that rent by employee named as CNEMAS (Computer & Network Equipment Management System ...
Imelda Pangaribuan, A Rahman, S Mauluddin   +2 more
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Continuous Information Systems

Information and Computation, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Information processing using a single dynamical node as complex system

Nature Communications, 2011
Novel methods for information processing are highly desired in our information-driven society. Inspired by the brain's ability to process information, the recently introduced paradigm known as 'reservoir computing' shows that complex networks can ...
L. Appeltant, M. C. Soriano, G. Van der Sande, J. Danckaert, S. Massar, J. Dambre, B. Schrauwen, C. Mirasso, Ingo Fischer   +8 more
semanticscholar   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Application of the Technology Readiness Index to Measure the Readiness of Personnel Information Systems for Village Employees in Tanjungmedar District

Jurnal Sisfokom
The development of information technology encourages village governments to adopt digital systems in improving services, including in the field of staffing.
Agun Guntara, Irfan Fadil, Fidi Supriadi, Aa Agus Mulyana   +3 more
doaj   +1 more source