Results 171 to 180 of about 31,728,436 (339)

INFORME CIBER. COMPORTAMIENTO INFORMACIONAL DEL INVESTIGADOR DEL FUTURO

open access: yesAnales de Documentación, 2008
British Library   +1 more
doaj  

Effective Uses of Information Systems [PDF]

open access: bronze, 1968
J.T. Raleigh   +2 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Smart cities: Advances in research - An information systems perspective

open access: yesInternational Journal of Information Management, 2019
Elvira Ismagilova   +3 more
semanticscholar   +1 more source

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