Results 191 to 200 of about 4,020,268 (318)

Spinal Cord Injury in India and The Need to Strengthen Injury Surveillance and Health Information Systems. [PDF]

Indian J Community Med
Thirumalai J, Ramalingam V.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Mapping disparities in diabetic eye exam adherence using geographic information systems. [PDF]

PLoS One
Dogra NS, Geiss MP, Gearinger T, Delmerico A, Ramchandran RS.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Usability evaluation methods for hospital information systems: a systematic review. [PDF]

BMC Health Serv Res
Dehghani Mahmoodabadi A, Dehghan H, Kimiafar K, Karami M, Mousavi Baigi SF, Farsi Mehrabadi M.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Using Health Information Systems to Support Behavioral Interventions in Local Contexts: Scoping Review. [PDF]

JMIR Med Inform
Yang X, Dijst M, Daams JG, Suhrcke M, Yang H, Cornet R.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Integration of Data and Information Systems Into the Health Data Strategy. [PDF]

JMIR Med Inform
Komenda M, Gregor J, Klimeš D, Pavlík T, Blaha M, Těšitelová V, Májek O, Ngo O, Chloupková R, Hejduk K, Šnajdrová L, Jarkovský J, Mužík J, Růžičková P, Válek V, Válek V, Dušek L.   +16 more
europepmc   +1 more source

A Conceptual Framework and Research Agenda for Harnessing Institutional Work in Green Information Systems

This study advances the field of Green Information Systems (IS) by conceptualizing the role of institutions (humanly devised rules, norms, and beliefs) in sustainability transitions with IS. We propose a framework for understanding how institutional work
Salmenautio, Niina, Lumivalo, Juuli, Elo, Jenny   +2 more
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