Results 211 to 220 of about 43,078,898 (347)

Paradox Lost? Firm-Level Evidence on the Returns to Information Systems Spending

, 1996
Erik Brynjolfsson, L. Hitt
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Contextual Barriers to Health Information Systems Optimization in Underserved Communities in Kenya: Qualitative Study Informed by Frugal Innovation and Information and Communication Technologies for Development. [PDF]

JMIR Form Res
Nyatuka D, Jabin MSR, Dionne-Morris L.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Integration of Data and Information Systems Into the Health Data Strategy.

JMIR Med Inform
Komenda M, Gregor J, Klimeš D, Pavlík T, Blaha M, Těšitelová V, Májek O, Ngo O, Chloupková R, Hejduk K, Šnajdrová L, Jarkovský J, Mužík J, Růžičková P, Válek V, Válek V, Dušek L.   +16 more
europepmc   +1 more source

The use of geographic information systems (GIS) in studying mental health service delivery: A scoping review. [PDF]

Glob Ment Health (Camb)
Biswal B, Paimapari R, Suresh A, Pacheco MG, Fernandes L, Gandhi Y, Patel V, Singla DR, Fernandes A, Velleman R, Lu C, Grundy C, Bhatia U, Nadkarni A.   +13 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Nexus between policy and practice in institutionalization of clinical information systems and knowledge management in developing health systems: Context of tertiary hospitals in Malawi. [PDF]

PLOS Digit Health
Kungwalo EC, Kanjo C, Kunyenje G, Chikumba PA.   +3 more
europepmc   +1 more source

Blockchain Technology in Business and Information Systems Research

Business & Information Systems Engineering, 2017
R. Beck, M. Avital, M. Rossi, J. Thatcher   +3 more
semanticscholar   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source