Results 101 to 110 of about 6,767,647 (299)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Effective k-nearest neighbor models for data classification enhancement

Journal of Big Data
Imbalanced class distributions and class overlaps are major problems that are often associated with the classifier’s decreased performance. To lessen their impact, the literature continues to introduce methods, including kNN extensions.
Ali A. Amer, Sri Devi Ravana, Riyaz Ahamed Ariyaluran Habeeb   +2 more
doaj   +1 more source

A flexible modeling framework to estimate interregional trade patterns and input-output accounts [PDF]

This study implements and tests a mathematical programming model to estimate interregional, interindustry transaction flows in a national system of economic regions based on an interregional accounting framework and initial information of interregional ...
Canning, Patrick, Wang, Zhi
core  

Contextuality and Information Systems: how the interplay between paradigms can help [PDF]

, 2009
Through this paper, we theorize on the meanings and roles of context in the study of information systems. The literatures of information systems and information science both explicitly conceptualize information systems (and there are multiple ...
Jarrahi, Mohammad Hossein, Sawyer, Steve
core  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Assessing green area changes in Najran City, Saudi Arabia (2013–2022) using hybrid deep learning techniques

Open Geosciences
Advances in remote sensing technology have facilitated the assessment of land vegetation and agricultural development using satellite images. This study’s normalized difference vegetation index (NDVI) is vital in assessing vegetation coverage and ...
Ali Elham, Alshari Eman A., Shamsan Ahlam, Alqhatani Abdulmajeed, Al-Wagih Khalil, Olayah Fekry, Senan Ebrahim Mohammed, Aljubayri Mohammed   +7 more
doaj   +1 more source

Using SimVenture in Computer Science & Information Systems Management [PDF]

A case study from the Developing Enterprising Students project, a strategic teaching and learning project at the University of Huddersfield. The case study is based on an interview with Helen Southall, Senior Lecturer in the department of Computer ...
Jensen, Kathrine, Yip, Daniel
core  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

ResViT HybridNet: a fusion of ResNet50 and Vision Transformer for banana leaf disease identification

Automatika
Banana leaf diseases such as Cordana, Sigatoka, and Pestalotiopsis significantly reduce crop yield and quality, necessitating accurate and early detection for effective management.
Vishnu Kant, Sheifali Gupta, Samar M. Alqhtani, M. A. Elmagzoub, Mana Saleh Al Reshan, Mousa Alalhareth, Asadullah Shaikh   +6 more
doaj   +1 more source

COLLABORATIVE SYSTEMS AND MATHEMATICAL MODELS FOR LEADING ECONOMIC PROCESSES [PDF]

A collaborative system is an interdisciplinary field located at the intersection of economics, computer science, management and sociology. These systems are focused on building connections between people, equipment and information.
Irina Barbu
core