Results 41 to 50 of about 4,635,546 (299)
Submap: conceptualising relational space using information technologies [PDF]
, 2015 “We are not building cities for people to live in; we are building cities for people to invest in” (Harvey, 2015)In the last three years, London boroughs have moved 50000 families out of their neighbourhoods as a result of soaring rents (The independent,
Giupponi, Noemi, Thomson, Craig
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Information Technologies in Genetics
Цифровая трансформация, 2016 The article describes and groups on directions the experience of information technologies in genetics. Currently a huge amount of data received in genetics as part of large-scale projects, and it requires processing.
N. A. Balashenko
doaj +2 more sources
Intellectual Solutions for Development of Information Technologies [PDF]
, 2017 With the development of computer technologies, the meaning invested in the notion of an information system changed. A modern information system is a set of information technologies aimed at supporting the life cycle of information and includes three ...
Komarova, O. I. +2 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Stand-alone solar optic device based on aps-photodeciver [PDF]
E3S Web of ConferencesThis paper discusses a detailed description of the design of a special physical device of a helioptocoupler aimed at receiving solar radiation with its subsequent conversion, as well as output in the form of an anomalously high photo-voltage.
Quldashov Obbosjon +5 more
doaj +1 more source
Recommendations for Using Online Social Networking Technologies to Reduce Inaccurate Online Health Information [PDF]
, 2011 This short report highlights patients' increasing use of the Internet and online social networking technologies to seek health information, and the consequences of gaining information from sites with biased or inaccurate health information. Reflecting on
Young, SD
core +1 more source